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Co-existence of BRAF(V600E) and TERT promoter mutations in papillary thyroid carcinoma is associated with tumor aggressiveness, but not with lymph node metastasis

BACKGROUND: Mutations of BRAF(V600E) and TERT promoters are associated with thyroid cancer development. This study further investigated association of these mutations with clinicopathological characteristics from patients with papillary thyroid carcinoma (PTC). METHODS: Tumor tissues from 342 PTC pa...

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Detalles Bibliográficos
Autores principales: Ren, Haoyu, Shen, Yifan, Hu, Daixing, He, Wei, Zhou, Jing, Cao, Yijia, Mao, Yu, Dou, Yi, Xiong, Wei, Xiao, Qi, Zhang, Yuhong, Su, Xinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937490/
https://www.ncbi.nlm.nih.gov/pubmed/29760568
http://dx.doi.org/10.2147/CMAR.S159583