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Mechanistic Insights into the Differential Catalysis by RheB and Its Mutants: Y35A and Y35A-D65A
[Image: see text] RheB GTPase is a Ras-related molecular switch, which regulates the mTOR signaling pathway by cycling between the active [guanosine triphosphate (GTP)] state and inactive [guanine diphosphate (GDP)] state. Impairment of GTPase activity because of mutations in several small GTPases i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937686/ https://www.ncbi.nlm.nih.gov/pubmed/29750207 http://dx.doi.org/10.1021/acsomega.7b01025 |