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miR-27a protects human mitral valve interstitial cell from TNF-α-induced inflammatory injury via up-regulation of NELL-1

MicroRNAs (miRNAs) have been reported to be associated with heart valve disease, which can be caused by inflammation. This study aimed to investigate the functional impacts of miR-27a on TNF-α-induced inflammatory injury in human mitral valve interstitial cells (hMVICs). hMVICs were subjected to 40...

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Detalles Bibliográficos
Autores principales: Chen, Honglei, Zhang, Zhixu, Zhang, Li, Wang, Junzhi, Zhang, Minghui, Zhu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937725/
https://www.ncbi.nlm.nih.gov/pubmed/29694513
http://dx.doi.org/10.1590/1414-431X20186997