Sphingosine 1-phosphate attenuates MMP2 and MMP9 in human anaplastic thyroid cancer C643 cells: Importance of S1P(2)

In anaplastic thyroid cancer C643 cells, sphingosine 1-phosphate (S1P) attenuates migration by activating the S1P(2) receptor and the Rho-ROCK pathway. In the present study, we show that stimulating C643 cells with S1P decreases the expression, secretion and activity of matrix metalloproteinase-2 (M...

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Detalles Bibliográficos
Autores principales: Asghar, Muhammad Yasir, Kemppainen, Kati, Lassila, Taru, Törnquist, Kid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937745/
https://www.ncbi.nlm.nih.gov/pubmed/29734379
http://dx.doi.org/10.1371/journal.pone.0196992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937745/
https://www.ncbi.nlm.nih.gov/pubmed/29734379
http://dx.doi.org/10.1371/journal.pone.0196992

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