Role of matrix metalloproteinases 2 and 9, toll-like receptor 4 and platelet-leukocyte aggregate formation in sepsis-associated thrombocytopenia

BACKGROUND: The development of thrombocytopenia in sepsis is a poor prognostic indicator associated with a significantly increased mortality risk. Mechanisms underlying this phenomenon remain to be clearly elucidated. Matrix metalloproteinases (MMPs) are enzymes that regulate the turnover of the ext...

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Detalles Bibliográficos
Autores principales: Larkin, Caroline M., Hante, Nadhim Kamil, Breen, Eamon P., Tomaszewski, Krzysztof A., Eisele, Simon, Radomski, Marek W., Ryan, Thomas A., Santos-Martinez, Maria-Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937753/
https://www.ncbi.nlm.nih.gov/pubmed/29734352
http://dx.doi.org/10.1371/journal.pone.0196478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937753/
https://www.ncbi.nlm.nih.gov/pubmed/29734352
http://dx.doi.org/10.1371/journal.pone.0196478

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