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Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages

BACKGROUND: Macrophages are one of the most important players in the tumor microenvironment. The polarization status of tumor associated macrophages into a pro-inflammatory type M1 or anti-inflammatory type M2 may influence cancer progression and patient survival. Extracellular vesicles (EVs) are me...

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Detalles Bibliográficos
Autores principales: Popēna, Ineta, Ābols, Artūrs, Saulīte, Līga, Pleiko, Kārlis, Zandberga, Elīna, Jēkabsons, Kaspars, Endzeliņš, Edgars, Llorente, Alicia, Linē, Aija, Riekstiņa, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937830/
https://www.ncbi.nlm.nih.gov/pubmed/29690889
http://dx.doi.org/10.1186/s12964-018-0229-y