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Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
BACKGROUND: Macrophages are one of the most important players in the tumor microenvironment. The polarization status of tumor associated macrophages into a pro-inflammatory type M1 or anti-inflammatory type M2 may influence cancer progression and patient survival. Extracellular vesicles (EVs) are me...
Autores principales: | Popēna, Ineta, Ābols, Artūrs, Saulīte, Līga, Pleiko, Kārlis, Zandberga, Elīna, Jēkabsons, Kaspars, Endzeliņš, Edgars, Llorente, Alicia, Linē, Aija, Riekstiņa, Una |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937830/ https://www.ncbi.nlm.nih.gov/pubmed/29690889 http://dx.doi.org/10.1186/s12964-018-0229-y |
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