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Molecular architecture of mouse and human pancreatic zymogen granules: protein components and their copy numbers

A molecular model of pancreatic zymogen granule (ZG) is critical for understanding its functions. We have extensively characterized the composition and membrane topology of rat ZG proteins. In this study, we report the development of targeted proteomics approaches to quantify representative mouse an...

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Detalles Bibliográficos
Autores principales: Lee, Jin-sook, Caruso, Joseph A., Hubbs, Garrett, Schnepp, Patricia, Woods, James, Fang, Jingye, Li, Chunying, Zhang, Kezhong, Stemmer, Paul M., Jena, Bhanu P., Chen, Xuequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937866/
https://www.ncbi.nlm.nih.gov/pubmed/29756009
http://dx.doi.org/10.1007/s41048-018-0055-1