ATP depletion during mitotic arrest induces mitotic slippage and APC/C(Cdh1)-dependent cyclin B1 degradation

ATP depletion inhibits cell cycle progression, especially during the G1 phase and the G2 to M transition. However, the effect of ATP depletion on mitotic progression remains unclear. We observed that the reduction of ATP after prometaphase by simultaneous treatment with 2-deoxyglucose and NaN(3) did...

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Detalles Bibliográficos
Autores principales: Park, Yun Yeon, Ahn, Ju-Hyun, Cho, Min-Guk, Lee, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938023/
https://www.ncbi.nlm.nih.gov/pubmed/29700288
http://dx.doi.org/10.1038/s12276-018-0069-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938023/
https://www.ncbi.nlm.nih.gov/pubmed/29700288
http://dx.doi.org/10.1038/s12276-018-0069-2

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