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ATP depletion during mitotic arrest induces mitotic slippage and APC/C(Cdh1)-dependent cyclin B1 degradation
ATP depletion inhibits cell cycle progression, especially during the G1 phase and the G2 to M transition. However, the effect of ATP depletion on mitotic progression remains unclear. We observed that the reduction of ATP after prometaphase by simultaneous treatment with 2-deoxyglucose and NaN(3) did...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938023/ https://www.ncbi.nlm.nih.gov/pubmed/29700288 http://dx.doi.org/10.1038/s12276-018-0069-2 |