Enhancement of 5-HT(2A) receptor function and blockade of Kv1.5 by MK801 and ketamine: implications for PCP derivative-induced disease models

MK801 and ketamine, which are phencyclidine (PCP) derivative N-methyl-d-aspartate receptor (NMDAr) blockers, reportedly enhance the function of 5-hydroxytryptamine (HT)-2A receptors (5-HT(2A)Rs). Both are believed to directly affect the pathogenesis of schizophrenia, as well as hypertension. 5-HT(2A...

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Detalles Bibliográficos
Autores principales: Lin, Haiyue, Kim, Jae Gon, Park, Sang Woong, Noh, Hyun Ju, Kim, Jeong Min, Yoon, Chang Yong, Woo, Nam-Sik, Kim, Bokyung, Il Cho, Sung, Choi, Bok Hee, Sung, Dong Jun, Bae, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938026/
https://www.ncbi.nlm.nih.gov/pubmed/29700292
http://dx.doi.org/10.1038/s12276-018-0073-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938026/
https://www.ncbi.nlm.nih.gov/pubmed/29700292
http://dx.doi.org/10.1038/s12276-018-0073-6

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