PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation

Defects in the PEX5 gene impair the import of peroxisomal matrix proteins, leading to nonfunctional peroxisomes and other associated pathological defects such as Zellweger syndrome. Although PEX5 regulates autophagy process in a stress condition, the mechanisms controlling autophagy by PEX5 under nu...

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Detalles Bibliográficos
Autores principales: Eun, So Young, Lee, Joon No, Nam, In-Koo, Liu, Zhi-qiang, So, Hong-Seob, Choe, Seong-Kyu, Park, RaeKil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938032/
https://www.ncbi.nlm.nih.gov/pubmed/29622767
http://dx.doi.org/10.1038/s12276-017-0007-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938032/
https://www.ncbi.nlm.nih.gov/pubmed/29622767
http://dx.doi.org/10.1038/s12276-017-0007-8

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