Circular RNA circ-4099 is induced by TNF-α and regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9 in intervertebral disc degeneration

Circular RNAs (circRNAs) play important roles in the initiation and development of different diseases. Here, we detected their role in intervertebral disc (IVD) degeneration. An Arraystar human circular RNA microarray assay was used to detect circRNAs in normal and degenerated human IVD nucleus pulp...

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Detalles Bibliográficos
Autores principales: Wang, Hua, He, Peiheng, Pan, Hehai, long, Jun, Wang, Jianru, Li, Zemin, Liu, Hui, Jiang, Weiying, Zheng, Zhaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938034/
https://www.ncbi.nlm.nih.gov/pubmed/29651107
http://dx.doi.org/10.1038/s12276-018-0056-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938034/
https://www.ncbi.nlm.nih.gov/pubmed/29651107
http://dx.doi.org/10.1038/s12276-018-0056-7

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