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Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesis

Colorectal cancer (CRC) is a disease involving a variety of genetic and environmental factors. Sirtuin-3 (Sirt3) is expressed at a low level in cancer tissues of CRC, but it is unclear how Sirt3 modulates colonic tumorigenesis. In this study, we found that gut microbiota play a central role in the r...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Wang, Xiao-lan, Zhou, Min, Kang, Chao, Lang, He-dong, Chen, Meng-ting, Hui, Suo-cheng, Wang, Bin, Mi, Man-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938040/
https://www.ncbi.nlm.nih.gov/pubmed/29650970
http://dx.doi.org/10.1038/s12276-017-0002-0