Exendin-4 ameliorates high glucose-induced fibrosis by inhibiting the secretion of miR-192 from injured renal tubular epithelial cells

Extracellular vesicles (EVs), which contain microRNA (miRNA), constitute a novel means of cell communication that may contribute to the inevitable expansion of renal fibrosis during diabetic kidney disease (DKD). Exendin-4 is effective for treating DKD through its action on GLP1R. However, the effec...

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Detalles Bibliográficos
Autores principales: Jia, Yijie, Zheng, Zongji, Guan, Meiping, Zhang, Qian, Li, Yang, Wang, Ling, Xue, Yaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938044/
https://www.ncbi.nlm.nih.gov/pubmed/29717107
http://dx.doi.org/10.1038/s12276-018-0084-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938044/
https://www.ncbi.nlm.nih.gov/pubmed/29717107
http://dx.doi.org/10.1038/s12276-018-0084-3

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