The proximal tubular α7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction

Activation of the α7 nicotinic acetylcholine receptor (α7nAChR) has been shown to attenuate excessive inflammation by inhibiting proinflammatory cytokines during ischemia–reperfusion (IR) injury; however, the underlying kidney-specific molecular mechanisms remain unclear. The protective action of α7...

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Detalles Bibliográficos
Autores principales: Kim, Hwajin, Kim, So Ra, Je, Jihyun, Jeong, Kyuho, Kim, Sooji, Kim, Hye Jung, Chang, Ki Churl, Park, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938048/
https://www.ncbi.nlm.nih.gov/pubmed/29674665
http://dx.doi.org/10.1038/s12276-018-0061-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938048/
https://www.ncbi.nlm.nih.gov/pubmed/29674665
http://dx.doi.org/10.1038/s12276-018-0061-x

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