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The proximal tubular α7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction
Activation of the α7 nicotinic acetylcholine receptor (α7nAChR) has been shown to attenuate excessive inflammation by inhibiting proinflammatory cytokines during ischemia–reperfusion (IR) injury; however, the underlying kidney-specific molecular mechanisms remain unclear. The protective action of α7...
Autores principales: | Kim, Hwajin, Kim, So Ra, Je, Jihyun, Jeong, Kyuho, Kim, Sooji, Kim, Hye Jung, Chang, Ki Churl, Park, Sang Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938048/ https://www.ncbi.nlm.nih.gov/pubmed/29674665 http://dx.doi.org/10.1038/s12276-018-0061-x |
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