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Glioblastoma-secreted soluble CD44 activates tau pathology in the brain

During aggressive tumor growth and migration, glioblastoma cells secrete diverse molecules and adhesion proteins to the extracellular matrix. Yet, the biochemical effects of the glioblastoma secretome in the brain remain largely unknown. Here we show that soluble CD44 secreted from glioblastoma cell...

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Detalles Bibliográficos
Autores principales: Lim, Sungsu, Kim, Dohee, Ju, Shinyeong, Shin, Seulgi, Cho, Il-joo, Park, Sung-Hye, Grailhe, Regis, Lee, Cheolju, Kim, Yun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938049/
https://www.ncbi.nlm.nih.gov/pubmed/29622771
http://dx.doi.org/10.1038/s12276-017-0008-7