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Therapeutic potential of a phospholipase D1 inhibitory peptide fused with a cell-penetrating peptide as a novel anti-asthmatic drug in a Der f 2-induced airway inflammation model

Asthma is a chronic lung disease that causes airflow obstruction due to airway inflammation. However, its therapeutics remain inadequate. We previously reported that phospholipase D1 (PLD1) is a key enzyme involved in the production of pro-inflammatory cytokines in airway inflammation induced by the...

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Detalles Bibliográficos
Autores principales: Lee, Yun Young, Lee, So Young, Park, Shin-Young, Choi, Hye-Jin, Kim, Eung-Gook, Han, Joong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938051/
https://www.ncbi.nlm.nih.gov/pubmed/29717122
http://dx.doi.org/10.1038/s12276-018-0083-4