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Therapeutic potential of a phospholipase D1 inhibitory peptide fused with a cell-penetrating peptide as a novel anti-asthmatic drug in a Der f 2-induced airway inflammation model
Asthma is a chronic lung disease that causes airflow obstruction due to airway inflammation. However, its therapeutics remain inadequate. We previously reported that phospholipase D1 (PLD1) is a key enzyme involved in the production of pro-inflammatory cytokines in airway inflammation induced by the...
Autores principales: | Lee, Yun Young, Lee, So Young, Park, Shin-Young, Choi, Hye-Jin, Kim, Eung-Gook, Han, Joong-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938051/ https://www.ncbi.nlm.nih.gov/pubmed/29717122 http://dx.doi.org/10.1038/s12276-018-0083-4 |
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