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Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13–RhoA–ROCK signaling pathway

The mechanism by which gastrin promotes pancreatic cancer cell metastasis is unclear. The process of directing polarized cancer cells toward the extracellular matrix is principally required for invasion and distant metastasis; however, whether gastrin can induce this process and its underlying mecha...

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Detalles Bibliográficos
Autores principales: Mu, Ganggang, Ding, Qianshan, Li, Hongyan, Zhang, Li, Zhang, Lingli, He, Ke, Wu, Lu, Deng, Yunchao, Yang, Dongmei, Wu, Lianlian, Xu, Ming, Zhou, Jie, Yu, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938061/
https://www.ncbi.nlm.nih.gov/pubmed/29717112
http://dx.doi.org/10.1038/s12276-018-0081-6