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Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13–RhoA–ROCK signaling pathway
The mechanism by which gastrin promotes pancreatic cancer cell metastasis is unclear. The process of directing polarized cancer cells toward the extracellular matrix is principally required for invasion and distant metastasis; however, whether gastrin can induce this process and its underlying mecha...
Autores principales: | Mu, Ganggang, Ding, Qianshan, Li, Hongyan, Zhang, Li, Zhang, Lingli, He, Ke, Wu, Lu, Deng, Yunchao, Yang, Dongmei, Wu, Lianlian, Xu, Ming, Zhou, Jie, Yu, Honggang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938061/ https://www.ncbi.nlm.nih.gov/pubmed/29717112 http://dx.doi.org/10.1038/s12276-018-0081-6 |
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