Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain

The lineage relationships among the hundreds of cell types generated during development are difficult to reconstruct. A recent method, GESTALT, used CRISPR-Cas9 barcode editing for large-scale lineage tracing, but was restricted to early development and did not identify cell types. Here we present s...

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Detalles Bibliográficos
Autores principales: Raj, Bushra, Wagner, Daniel E., McKenna, Aaron, Pandey, Shristi, Klein, Allon M., Shendure, Jay, Gagnon, James A., Schier, Alexander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938111/
https://www.ncbi.nlm.nih.gov/pubmed/29608178
http://dx.doi.org/10.1038/nbt.4103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938111/
https://www.ncbi.nlm.nih.gov/pubmed/29608178
http://dx.doi.org/10.1038/nbt.4103

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