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Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain
The lineage relationships among the hundreds of cell types generated during development are difficult to reconstruct. A recent method, GESTALT, used CRISPR-Cas9 barcode editing for large-scale lineage tracing, but was restricted to early development and did not identify cell types. Here we present s...
Autores principales: | Raj, Bushra, Wagner, Daniel E., McKenna, Aaron, Pandey, Shristi, Klein, Allon M., Shendure, Jay, Gagnon, James A., Schier, Alexander F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938111/ https://www.ncbi.nlm.nih.gov/pubmed/29608178 http://dx.doi.org/10.1038/nbt.4103 |
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