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Genomewide association study identifies a novel locus for cannabis dependence

Despite moderate heritability, only one study has identified genomewide significant loci for cannabis-related phenotypes. We conducted meta-analyses of genomewide association study (GWAS) data on 2,080 DSM-IV cannabis dependent cases and 6,435 cannabis exposed controls of European descent. A cluster...

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Detalles Bibliográficos
Autores principales: Agrawal, Arpana, Chou, Yi-Ling, Carey, Caitlin E., Baranger, David A. A., Zhang, Bo, Sherva, Richard, Wetherill, Leah, Kapoor, Manav, Wang, Jen-Chyong, Bertelsen, Sarah, Anokhin, Andrey P, Hesselbrock, Victor, Kramer, John, Lynskey, Michael T., Meyers, Jacquelyn L., Nurnberger, John I, Rice, John P., Tischfield, Jay, Bierut, Laura J., Degenhardt, Louisa, Farrer, Lindsay A, Gelernter, Joel, Hariri, Ahmad R., Heath, Andrew C., Kranzler, Henry R., Madden, Pamela A. F., Martin, Nicholas G., Montgomery, Grant W, Porjesz, Bernice, Wang, Ting, Whitfield, John B., Edenberg, Howard J., Foroud, Tatiana, Goate, Alison M., Bogdan, Ryan, Nelson, Elliot C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938138/
https://www.ncbi.nlm.nih.gov/pubmed/29112194
http://dx.doi.org/10.1038/mp.2017.200