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Adiponectin deficiency-induced diabetes increases TNFα and FFA via downregulation of PPARα

Expression of peroxisome proliferator-activated receptor (PPAR) α was investigated in adiponectin knockout mice to elucidate the relationship between PPARα and adiponectin deficiency-induced diabetes. Adiponectin knockout (Adp(−/−)) mice were generated by gene targeting. Glucose tolerance test (GTT)...

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Detalles Bibliográficos
Autores principales: HASHIMOTO, Haruo, YAMAMOTO, Masafumi, SUGIURA, Emika, ABE, Hayato, KAGAWA, Takahiro, GOTO, Motohito, TAKAHASHI, Ri-ichi, AKIMOTO, Toshio, SUEMIZU, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938197/
https://www.ncbi.nlm.nih.gov/pubmed/29445073
http://dx.doi.org/10.1292/jvms.17-0641