Cargando…

Adiponectin deficiency-induced diabetes increases TNFα and FFA via downregulation of PPARα

Expression of peroxisome proliferator-activated receptor (PPAR) α was investigated in adiponectin knockout mice to elucidate the relationship between PPARα and adiponectin deficiency-induced diabetes. Adiponectin knockout (Adp(−/−)) mice were generated by gene targeting. Glucose tolerance test (GTT)...

Descripción completa

Detalles Bibliográficos
Autores principales:	HASHIMOTO, Haruo, YAMAMOTO, Masafumi, SUGIURA, Emika, ABE, Hayato, KAGAWA, Takahiro, GOTO, Motohito, TAKAHASHI, Ri-ichi, AKIMOTO, Toshio, SUEMIZU, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2018
Materias:	Laboratory Animal Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938197/ https://www.ncbi.nlm.nih.gov/pubmed/29445073 http://dx.doi.org/10.1292/jvms.17-0641

Ejemplares similares

Development of blastocyst complementation technology without contributions to gametes and the brain
por: Hashimoto, Haruo, et al.
Publicado: (2019)

Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner
por: Sun, Zongguo, et al.
Publicado: (2019)

TNF-α-mediated podocyte injury via the apoptotic death receptor pathway in a mouse model of IgA nephropathy
por: Wan, Qiang, et al.
Publicado: (2022)

Tracheal growth assessment in mongrel puppies (dogs) through multidetector CT
por: Soriano-Rosales, Rosa Eugenia, et al.
Publicado: (2018)

Megaesophagus Is a Major Pathological Condition in Rats With a Large Deletion in the Rbm20 Gene
por: Schwahn, Denise J., et al.
Publicado: (2019)

Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice
por: Finesso, Giovanni, et al.
Publicado: (2023)

A method for scoring 4-nitroquinoline 1-oxide-induced murine esophageal squamous neoplasia
por: Aziz, Zaryab, et al.
Publicado: (2023)

Positive correlation between renal tubular flattening and renal tubular injury/interstitial fibrosis in murine kidney disease models
por: TAKAHASHI, Yuki, et al.
Publicado: (2021)

Mitotic spindle positioning protein (MISP) deficiency exacerbates dextran sulfate sodium (DSS)-induced colitis in mice
por: HIURA, Koki, et al.
Publicado: (2022)

Susceptibility to adriamycin-induced hepatotoxicity in mice depends on PRKDC polymorphism
por: WATANABE, Masaki, et al.
Publicado: (2023)

Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing
por: MARUSUGI, Kiyoma, et al.
Publicado: (2016)

Evaluation of mouse red blood cell and platelet counting with an automated hematology analyzer
por: FUKUDA, Teruko, et al.
Publicado: (2017)

Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner
por: ITOH, Tadashi, et al.
Publicado: (2020)

IGF-I attenuates FFA-induced activation of JNK1 phosphorylation and TNFα expression in human subcutaneous preadipocytes
por: Neacsu, Otilia, et al.
Publicado: (2013)

Prevalence of murine astrovirus in laboratory animal facilities in Japan
por: MORITA, Hanako, et al.
Publicado: (2020)

Time-of-Day-Dependent Variations of Scratching Behavior and Transepidermal Water Loss in Mice that Developed Atopic Dermatitis
por: OHMORI, Keitaro, et al.
Publicado: (2014)

Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells
por: Onodera, Toshiharu, et al.
Publicado: (2023)

In vivo characterization of rate-dependent impact on the QT interval of microminipig assessed by atrial electrical pacing: Development of correction formulae of QT interval
por: KAMBAYASHI, Ryuichi, et al.
Publicado: (2019)

CCL2 induces neural stem cell proliferation and neuronal differentiation in Niemann-Pick type C mice
por: HONG, Yu Ri, et al.
Publicado: (2015)

Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) overexpression alleviates endoplasmic reticulum stress after acute kidney injury
por: Pan, Hao, et al.
Publicado: (2022)

Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats
por: Pan, Xiaoxia, et al.
Publicado: (2015)

Ontogenic and morphological study of gonadal formation in genetically-modified sex reversal XY(POS) mice
por: UMEMURA, Yuria, et al.
Publicado: (2015)

EID3 Promotes Glioma Cell Proliferation and Survival by Inactivating AMPKα1
por: Xiang, Yaoxian, et al.
Publicado: (2022)

Analysis of the cancer genome atlas (TCGA) database identifies an inverse relationship between interleukin-13 receptor α1 and α2 gene expression and poor prognosis and drug resistance in subjects with glioblastoma multiforme
por: Han, Jing, et al.
Publicado: (2017)

Relationship between adiponectin, TNFα, and SHBG in prepubertal children with obesity
por: Ramon-Krauel, Marta, et al.
Publicado: (2021)

The Role Of Adiponectin, TNF-α And Glutathione In The Pathogenesis And Evolution Of Type 1 Diabetes
por: Szabo, Csilla Enikő, et al.
Publicado: (2019)

Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis
por: Wu, Jun, et al.
Publicado: (2022)

MicroRNA-122-5p ameliorates tubular injury in diabetic nephropathy via FIH-1/HIF-1α pathway
por: Cheng, Li, et al.
Publicado: (2022)

PPAR γ/TLR4/TGF-β1 axis mediates the protection effect of erythropoietin on cyclosporin A-induced chronic nephropathy in rat
por: Liu, Bin, et al.
Publicado: (2020)

Development of an ELISA Using a Recombinant P46-Like Lipoprotein for Diagnosis of Mycoplasma pulmonis Infection in Rodents
por: ASANO, Atsushi, et al.
Publicado: (2013)

The Effect of L-Carnitine on Oxidative Stress Responses of Experimental Contrast-Induced Nephropathy in Rats
por: BOYACIOGLU, Murat, et al.
Publicado: (2013)

New Visible Endotracheal Intubation Method Using the Endoscope System for Mice Inhalational Anesthesia
por: KONNO, Kenjiro, et al.
Publicado: (2014)

Anesthetic Effect of a Combination of Medetomidine-Midazolam-Butorphanol in Cynomolgus Monkeys (Macaca fascicularis)
por: OCHI, Takehiro, et al.
Publicado: (2014)

Rolling Nagoya Mouse Strain (PROD-rol/rol) with Classic Piebald Mutation
por: YOSHIMOTO, Takuro, et al.
Publicado: (2014)

Repression of Hepatic Cytochrome P450 2D Expression in Mice during Babesia microti Infection
por: SHIMAMOTO, Yoshinori, et al.
Publicado: (2014)

Proteomic Analysis of Testicular Ischemia-Reperfusion Injury in Rats
por: OUH, In-Ohk, et al.
Publicado: (2013)

IL-10 Gene Polymorphisms and Their Association with Immune Traits in Four Rabbit Populations
por: WAN, Xiaoying, et al.
Publicado: (2013)

Effects of Polyethylene Glycol Administration and Bone Marrow Stromal Cell Transplantation Therapy in Spinal Cord Injury Mice
por: ODA, Yasutaka, et al.
Publicado: (2013)

Screening for Intestinal Microflora Influencing Superoxide Dismutase Activity in Mouse Cecal Mucosa
por: DOBASHI, Yuu, et al.
Publicado: (2013)

Genetic analysis of low survival rate of pups in RR/Sgn inbred mice
por: SUTO, Jun-ichi
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0p1rc585g39rrom8jmhlhaset1