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Freeze-dried equine-derived redback spider antivenom: a local irritation study by intramuscular injection in rabbits and a repeated-dose toxicity study in rats

The redback spider (Latrodectus hasseltii) is nonindigenous to Japan but has now spread throughout the country. Bites to humans are rare but can be fatal. We prepared freeze-dried redback spider antivenom for therapeutic use against bites in Japan by immunization of horse plasma. This study included...

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Detalles Bibliográficos
Autores principales: Yamamoto, Akihiko, Harano, Satomi, Shinya, Noriko, Nagano, Ayataka, Miyatsu, Yoshinobu, Sawabe, Kyouko, Matsumura, Takayuki, Ato, Manabu, Takahashi, Motohide, Taki, Hisashi, Hifumi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938211/
https://www.ncbi.nlm.nih.gov/pubmed/29749999
http://dx.doi.org/10.1293/tox.2017-0053