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Freeze-dried equine-derived redback spider antivenom: a local irritation study by intramuscular injection in rabbits and a repeated-dose toxicity study in rats
The redback spider (Latrodectus hasseltii) is nonindigenous to Japan but has now spread throughout the country. Bites to humans are rare but can be fatal. We prepared freeze-dried redback spider antivenom for therapeutic use against bites in Japan by immunization of horse plasma. This study included...
Autores principales: | Yamamoto, Akihiko, Harano, Satomi, Shinya, Noriko, Nagano, Ayataka, Miyatsu, Yoshinobu, Sawabe, Kyouko, Matsumura, Takayuki, Ato, Manabu, Takahashi, Motohide, Taki, Hisashi, Hifumi, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938211/ https://www.ncbi.nlm.nih.gov/pubmed/29749999 http://dx.doi.org/10.1293/tox.2017-0053 |
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