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Functional promoter rs189037 variant of ATM is associated with decrease in lung diffusing capacity after irradiation for non–small-cell lung cancer

OBJECTIVE: Single-nucleotide polymorphisms (SNPs) in the ataxia telangiectasia–mutated gene ATM have been linked with pneumonitis after radiotherapy for lung cancer but have not been evaluated in terms of pulmonary function impairment. Here we investigated potential associations between SNPs in ATM...

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Detalles Bibliográficos
Autores principales: Lopez Guerra, Jose Luis, Song, Yi-Peng, Nguyen, Quynh-Nhu, Gomez, Daniel R., Liao, Zhongxing, Xu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938288/
https://www.ncbi.nlm.nih.gov/pubmed/29756124
http://dx.doi.org/10.1016/j.cdtm.2018.02.006