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A Promising IFN-Deficient System to Manufacture IFN-Sensitive Influenza Vaccine Virus

Interferon (IFN)-sensitive and replication-incompetent influenza viruses are likely to be the alternatives to inactivated and attenuated virus vaccines. Some IFN-sensitive influenza vaccine candidates with modified non-structural protein 1 (NS1) are highly attenuated in IFN-competent hosts but induc...

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Detalles Bibliográficos
Autores principales: Chen, Can, Fan, Wenhui, Li, Jing, Zheng, Weinan, Zhang, Shuang, Yang, Limin, Liu, Di, Liu, Wenjun, Sun, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938381/
https://www.ncbi.nlm.nih.gov/pubmed/29765910
http://dx.doi.org/10.3389/fcimb.2018.00127