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A Promising IFN-Deficient System to Manufacture IFN-Sensitive Influenza Vaccine Virus
Interferon (IFN)-sensitive and replication-incompetent influenza viruses are likely to be the alternatives to inactivated and attenuated virus vaccines. Some IFN-sensitive influenza vaccine candidates with modified non-structural protein 1 (NS1) are highly attenuated in IFN-competent hosts but induc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938381/ https://www.ncbi.nlm.nih.gov/pubmed/29765910 http://dx.doi.org/10.3389/fcimb.2018.00127 |