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Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty

Frailty is a complex aging phenotype associated with increased vulnerability to disability and death. Understanding the biological antecedents of frailty may provide clues to healthy aging. The genome-wide association study hotspot, 9p21-23 region, is a risk locus for a number of age-related complex...

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Detalles Bibliográficos
Autores principales: Sathyan, Sanish, Barzilai, Nir, Atzmon, Gil, Milman, Sofiya, Ayers, Emmeline, Verghese, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938407/
https://www.ncbi.nlm.nih.gov/pubmed/29765957
http://dx.doi.org/10.3389/fmed.2018.00105