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Immunization With Skp Delivered on Outer Membrane Vesicles Protects Mice Against Enterotoxigenic Escherichia coli Challenge

Outer membrane vesicles (OMVs) are promising vaccine components because they combine antigen and adjuvant in a single formulation. Detoxified Salmonella enterica strains that express penta-acylated lipid A retain OMV immunogenicity but with reduced reactogenicity. We have previously shown that a rec...

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Detalles Bibliográficos
Autores principales: Hays, Michael P., Houben, Diane, Yang, Yang, Luirink, Joen, Hardwidge, Philip R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938412/
https://www.ncbi.nlm.nih.gov/pubmed/29765911
http://dx.doi.org/10.3389/fcimb.2018.00132