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Chemical compound-based direct reprogramming for future clinical applications

Recent studies have revealed that a combination of chemical compounds enables direct reprogramming from one somatic cell type into another without the use of transgenes by regulating cellular signaling pathways and epigenetic modifications. The generation of induced pluripotent stem (iPS) cells gene...

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Detalles Bibliográficos
Autores principales: Takeda, Yukimasa, Harada, Yoshinori, Yoshikawa, Toshikazu, Dai, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938430/
https://www.ncbi.nlm.nih.gov/pubmed/29739872
http://dx.doi.org/10.1042/BSR20171650