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A trial like ALIC(4)E: why design a platform, response-adaptive, open, randomised controlled trial of antivirals for influenza-like illness?

ALIC(4)E is the first publicly funded, multicountry, pragmatic study determining whether antivirals should be routinely prescribed for influenza-like illness in primary care. The trial aims to go beyond determining the average treatment effect in a population to determining effects in patients with...

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Detalles Bibliográficos
Autores principales: Butler, Christopher C., Coenen, Samuel, Saville, Benjamin R., Cook, Johanna, van der Velden, Alike, Homes, Jane, de Jong, Menno, Little, Paul, Goossens, Herman, Beutels, Philippe, Ieven, Margareta, Francis, Nick, Moons, Pieter, Bongard, Emily, Verheij, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938489/
https://www.ncbi.nlm.nih.gov/pubmed/29761108
http://dx.doi.org/10.1183/23120541.00046-2018