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A trial like ALIC(4)E: why design a platform, response-adaptive, open, randomised controlled trial of antivirals for influenza-like illness?
ALIC(4)E is the first publicly funded, multicountry, pragmatic study determining whether antivirals should be routinely prescribed for influenza-like illness in primary care. The trial aims to go beyond determining the average treatment effect in a population to determining effects in patients with...
Autores principales: | Butler, Christopher C., Coenen, Samuel, Saville, Benjamin R., Cook, Johanna, van der Velden, Alike, Homes, Jane, de Jong, Menno, Little, Paul, Goossens, Herman, Beutels, Philippe, Ieven, Margareta, Francis, Nick, Moons, Pieter, Bongard, Emily, Verheij, Theo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938489/ https://www.ncbi.nlm.nih.gov/pubmed/29761108 http://dx.doi.org/10.1183/23120541.00046-2018 |
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