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Mitochondrial DNA copy number instability in ERBB2-amplified breast cancer tumors

Increase in the copy number of ERBB2, a Tyrosine Kinase Receptor (TKR) leads to the overexpression of oncogene product and consequently uncontrolled cell proliferation which has been reported in different aggressive cancers with mitochondrial malfunctions. Although, amplification of ERBB2 has been r...

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Detalles Bibliográficos
Autores principales: Ebrahimi, Elmira, Almasi-Hashiani, Amir, Ghaffari, Kimia, Shirkoohi, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938539/
https://www.ncbi.nlm.nih.gov/pubmed/29743853
http://dx.doi.org/10.17179/excli2017-819