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BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer

The bromodomain-containing protein 7 (BRD7) was first identified as a tumor suppressor in nasopharyngeal carcinoma and has critical roles in cancer development and progression. However, the regulatory roles and mechanisms of BRD7 in cancer metabolism are still unknown. In this study, we demonstrated...

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Detalles Bibliográficos
Autores principales: Niu, Weihong, Luo, Yanwei, Wang, Xinye, Zhou, Yao, Li, Hui, Wang, Heran, Fu, Yaojie, Liu, Shanshan, Yin, Shanghelin, Li, Jianglei, Zhao, Ran, Liu, Yukun, Fan, Songqing, Li, Zheng, Xiong, Wei, Li, Xiaoling, Li, Guiyuan, Ren, Caiping, Tan, Ming, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938698/
https://www.ncbi.nlm.nih.gov/pubmed/29725006
http://dx.doi.org/10.1038/s41419-018-0536-7