WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia

Liver cancer is one of the most lethal malignancies with very poor prognosis once diagnosed. The most common form of liver cancer is hepatocellular carcinoma (HCC). The WW domain-containing oxidoreductase (WWOX) is a large gene that is often perturbed in a wide variety of tumors, including HCC. WWOX...

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Detalles Bibliográficos
Autores principales: Abu-Remaileh, Muhannad, Khalaileh, Abed, Pikarsky, Eli, Aqeilan, Rami I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938702/
https://www.ncbi.nlm.nih.gov/pubmed/29724996
http://dx.doi.org/10.1038/s41419-018-0510-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938702/
https://www.ncbi.nlm.nih.gov/pubmed/29724996
http://dx.doi.org/10.1038/s41419-018-0510-4

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