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Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice

Tctn3 belongs to the Tectonic (Tctn) family and is a single-pass membrane protein localized at the transition zone of primary cilia as an important component of ciliopathy-related protein complexes. Previous studies showed that mutations in Tctn1 and Tctn2, two members of the tectonic family, have b...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Zhang, Yingying, Dong, Hongli, Gong, Siyi, Wei, Bin, Luo, Man, Wang, Hongyan, Wu, Xiaohui, Liu, Wei, Xu, Xingshun, Zheng, Yufang, Sun, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938703/
https://www.ncbi.nlm.nih.gov/pubmed/29725084
http://dx.doi.org/10.1038/s41419-018-0563-4