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Nucleolar TRF2 attenuated nucleolus stress-induced HCC cell-cycle arrest by altering rRNA synthesis

The nucleolus is an important organelle that is responsible for the biogenesis of ribosome RNA (rRNA) and ribosomal subunits assembly. It is also deemed to be the center of metabolic control, considering the critical role of ribosomes in protein translation. Perturbations of rRNA synthesis are close...

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Detalles Bibliográficos
Autores principales: Yuan, Fuwen, Xu, Chenzhong, Li, Guodong, Tong, Tanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938709/
https://www.ncbi.nlm.nih.gov/pubmed/29725012
http://dx.doi.org/10.1038/s41419-018-0572-3