Biomaterial surface energy-driven ligand assembly strongly regulates stem cell mechanosensitivity and fate on very soft substrates

Although mechanisms of cell–material interaction and cellular mechanotransduction are increasingly understood, the mechanical insensitivity of mesenchymal cells to certain soft amorphous biomaterial substrates has remained largely unexplained. We reveal that surface energy-driven supramolecular liga...

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Detalles Bibliográficos
Autores principales: Razafiarison, Tojo, Holenstein, Claude N., Stauber, Tino, Jovic, Milan, Vertudes, Edward, Loparic, Marko, Kawecki, Maciej, Bernard, Laetitia, Silvan, Unai, Snedeker, Jess G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939054/
https://www.ncbi.nlm.nih.gov/pubmed/29666253
http://dx.doi.org/10.1073/pnas.1704543115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939054/
https://www.ncbi.nlm.nih.gov/pubmed/29666253
http://dx.doi.org/10.1073/pnas.1704543115

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