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Biomaterial surface energy-driven ligand assembly strongly regulates stem cell mechanosensitivity and fate on very soft substrates
Although mechanisms of cell–material interaction and cellular mechanotransduction are increasingly understood, the mechanical insensitivity of mesenchymal cells to certain soft amorphous biomaterial substrates has remained largely unexplained. We reveal that surface energy-driven supramolecular liga...
Autores principales: | Razafiarison, Tojo, Holenstein, Claude N., Stauber, Tino, Jovic, Milan, Vertudes, Edward, Loparic, Marko, Kawecki, Maciej, Bernard, Laetitia, Silvan, Unai, Snedeker, Jess G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939054/ https://www.ncbi.nlm.nih.gov/pubmed/29666253 http://dx.doi.org/10.1073/pnas.1704543115 |
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