Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species

Bacterial genomes encode numerous cryptic biosynthetic gene clusters (BGCs) that represent a largely untapped source of drugs or pesticides. Mining of the cryptic products is limited by the unavailability of streamlined genetic tools in native producers. Precise genome engineering using bacteriophag...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Zhou, Haibo, Chen, Hanna, Jing, Xiaoshu, Zheng, Wentao, Li, Ruijuan, Sun, Tao, Liu, Jiaqi, Fu, Jun, Huo, Liujie, Li, Yue-zhong, Shen, Yuemao, Ding, Xiaoming, Müller, Rolf, Bian, Xiaoying, Zhang, Youming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939090/
https://www.ncbi.nlm.nih.gov/pubmed/29666226
http://dx.doi.org/10.1073/pnas.1720941115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939090/
https://www.ncbi.nlm.nih.gov/pubmed/29666226
http://dx.doi.org/10.1073/pnas.1720941115

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