Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor

Lysosomes have an important role in cellular protein and organelle quality control, metabolism, and signaling. On the surface of lysosomes, the PIKfyve/Fab1 complex generates phosphatidylinositol 3,5-bisphosphate, PI-3,5-P(2), which is critical for lysosomal membrane homeostasis during acute osmotic...

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Detalles Bibliográficos
Autores principales: Malia, PC, Numrich, Johannes, Nishimura, Taki, González Montoro, Ayelén, Stefan, Christopher J., Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939101/
https://www.ncbi.nlm.nih.gov/pubmed/29674454
http://dx.doi.org/10.1073/pnas.1722517115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939101/
https://www.ncbi.nlm.nih.gov/pubmed/29674454
http://dx.doi.org/10.1073/pnas.1722517115

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