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FUNNEL-GSEA: FUNctioNal ELastic-net regression in time-course gene set enrichment analysis

MOTIVATION: Gene set enrichment analyses (GSEAs) are widely used in genomic research to identify underlying biological mechanisms (defined by the gene sets), such as Gene Ontology terms and molecular pathways. There are two caveats in the currently available methods: (i) they are typically designed...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Topham, David J, Thakar, Juilee, Qiu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939227/
https://www.ncbi.nlm.nih.gov/pubmed/28334094
http://dx.doi.org/10.1093/bioinformatics/btx104