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Pharmacological Modulation of AMPAR Rescues Intellectual Disability-Like Phenotype in Tm4sf2(−/y) Mice
Intellectual disability affects 2–3% of the world's population and typically begins during childhood, causing impairments in social skills and cognitive abilities. Mutations in the TM4SF2 gene, which encodes the TSPAN7 protein, cause a severe form of intellectual disability, and currently, no t...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939231/ https://www.ncbi.nlm.nih.gov/pubmed/28968657 http://dx.doi.org/10.1093/cercor/bhx221 |