Pharmacological Modulation of AMPAR Rescues Intellectual Disability-Like Phenotype in Tm4sf2(−/y) Mice

Intellectual disability affects 2–3% of the world's population and typically begins during childhood, causing impairments in social skills and cognitive abilities. Mutations in the TM4SF2 gene, which encodes the TSPAN7 protein, cause a severe form of intellectual disability, and currently, no t...

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Detalles Bibliográficos
Autores principales: Murru, Luca, Vezzoli, Elena, Longatti, Anna, Ponzoni, Luisa, Falqui, Andrea, Folci, Alessandra, Moretto, Edoardo, Bianchi, Veronica, Braida, Daniela, Sala, Mariaelvina, D'Adamo, Patrizia, Bassani, Silvia, Francolini, Maura, Passafaro, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939231/
https://www.ncbi.nlm.nih.gov/pubmed/28968657
http://dx.doi.org/10.1093/cercor/bhx221

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