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Neogambogic Acid Suppresses Receptor Activator of Nuclear Factor κB Ligand (RANKL)-Induced Osteoclastogenesis by Inhibiting the JNK and NF-κB Pathways in Mouse Bone Marrow-Derived Monocyte/Macrophages

BACKGROUND: Neogambogic acid (NGA) is used in traditional Chinese medicine. The aim of this study was to investigate the effects of NGA on gene signaling pathways involved in osteoclastogenesis in mouse bone marrow-derived monocyte/macrophages (BMMs) and on bone resorption in vitro. MATERIAL/METHODS...

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Detalles Bibliográficos
Autores principales: Jin, Gu, Wang, Fang-Fang, Li, Tao, Jia, Dong-Dong, Shen, Yong, Xu, Hai-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939603/
https://www.ncbi.nlm.nih.gov/pubmed/29698379
http://dx.doi.org/10.12659/MSM.909651