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Neogambogic Acid Suppresses Receptor Activator of Nuclear Factor κB Ligand (RANKL)-Induced Osteoclastogenesis by Inhibiting the JNK and NF-κB Pathways in Mouse Bone Marrow-Derived Monocyte/Macrophages
BACKGROUND: Neogambogic acid (NGA) is used in traditional Chinese medicine. The aim of this study was to investigate the effects of NGA on gene signaling pathways involved in osteoclastogenesis in mouse bone marrow-derived monocyte/macrophages (BMMs) and on bone resorption in vitro. MATERIAL/METHODS...
Autores principales: | Jin, Gu, Wang, Fang-Fang, Li, Tao, Jia, Dong-Dong, Shen, Yong, Xu, Hai-Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939603/ https://www.ncbi.nlm.nih.gov/pubmed/29698379 http://dx.doi.org/10.12659/MSM.909651 |
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